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Updated: May 23, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
NHC/Pd Synergistically Catalyzed Direct Aerobic Oxidative Allylic Esterification of Aldehydes
Chhanda Debnath1, Shikha Gandhi1
1Department of Chemical Sciences, Indian Institute of Science Education and Research Berhampur, Berhampur, Odisha 760010, India.
Abstract:
N-Heterocyclic carbene (NHC)-mediated aerobic oxidation of aldehydes has gained interest in recent years. However, its application in NHC/Pd synergistic catalysis has been unexplored. We have developed a strategy to synthesize allylic esters directly from aldehydes and Morita-Baylis-Hillman (MBH) carbonates using NHC/Pd synergistic (cooperative) catalysis under aerobic conditions. This transformation gives access to the selective formation of multifunctionalized E-alkenes by β-attack on the MBH carbonates. This catalytic system also allows the use of water as a cosolvent and air as the sole green oxidant.
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