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Updated: May 23, 2025
Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
A case of late-onset psychosis secondary to traumatic brain injury difficult to differentiate from delirium
Tomonobu Kato1,2, Takashi Tsujii1, Hisashi Kida1,2
1Department of Neuropsychiatry Asaka Hospital Koriyama Fukushima Japan.
Background:
Traumatic brain injury (TBI) is a brain injury caused by external forces and has a prevalence of 432 cases (95% uncertainty interval [UI]: 413-452) per 100,000 people in Japan. Previous studies have indicated that TBI is associated with numerous psychiatric disorders, including psychosis.
Case Presentation:
A 70-year-old male with a history of diabetes, bipolar disorder, and TBI sustained at the age of 51 years presented with late-onset psychotic symptoms. This case highlights the delirium-like fluctuating nature of psychotic symptoms and their successful management with risperidone.
Conclusion:
Late-onset psychotic disorders due to TBI can emerge long after initial injury and require careful and continuous monitoring.
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