Related Experiment Video
Updated: May 23, 2025

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
Atypical Guillain-Barré Syndrome in a Young Adult: Diagnostic Challenges and Lessons Learned
Hannah Becker1, Edena R Khoshaba2, David A Ansell2
1Medical School, Rush University Medical Center, Chicago, USA.
Abstract:
Guillain-Barré Syndrome (GBS) is a rare, immune-mediated polyneuropathy that typically presents with ascending weakness, areflexia, and sensory disturbances. This case highlights an atypical presentation of GBS in an 18-year-old female, whose initial symptoms included primarily sensory deficits following routine exercise. The diagnostic process was complicated by unremarkable initial laboratory and imaging findings, but cerebrospinal fluid analysis revealed albuminocytologic dissociation, and electromyography confirmed acute demyelinating polyneuropathy. This case underscores the diagnostic challenges posed by atypical variants of GBS, the importance of thorough neurological evaluation, and the critical role of timely intervention in optimizing outcomes.
Related Concept Videos
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...

