Cannabis and Dermatological Implications: A Traditional Review of Adverse Cutaneous Reactions and Systemic Risks

The growing use of cannabis for both recreational and medicinal purposes has raised concerns about its cutaneous adverse effects. While systemic implications of cannabis are widely reported, dermatological manifestations remain underrecognized and underreported. This review aims to consolidate existing literature on cannabis-related dermatological complications, including allergic contact dermatitis, urticaria, Stevens-Johnson syndrome (SJS), and cannabis-induced arteritis. Emphasis is placed on mechanisms involving the endocannabinoid system in the skin, case reports of dermatological reactions, and implications for clinical dermatology. A structured methodology was applied to source peer-reviewed articles from databases including PubMed and Scopus, selecting studies published between 2000 and 2024 that directly addressed dermatological outcomes of cannabis use. Findings suggest a growing need for clinician awareness of cannabis as a potential etiologic agent in dermatological pathology. Future dermatology-focused research is essential to understand causality, diagnostic criteria, and effective treatment strategies.