Related Experiment Video
Updated: May 23, 2025

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
Published on: February 15, 2022
Relationship between psychological resilience, cognitive flexibility and post-traumatic growth level in patients with
Changzheng Zhao1, Lancai Zhou2, Haixia Gao1
1Intensive Care Unit, Shandong Public Health Clinical Center, Jinan, Shandong, China.
Objective:
Continuous renal replacement therapy (CRRT) is the primary treatment for severe sepsis and has been shown to reduce patient mortality. Patients with severe sepsis who receive CRRT frequently experience significant physical and psychological distress, manifesting as shame, social withdrawal, and abnormal cognitive moods. This study aimed to explore the relationship between psychological resilience, cognitive flexibility, and post-traumatic growth (PTG) levels in patients with severe sepsis treated with CRRT.
Methods:
From January to October 2024, patients with severe sepsis who were treated with CRRT in our hospital were selected by convenience sampling as the research object. The Connor-Davidson Resilience Scale (CDRISC), Cognitive Flexibility Scale, and Post-Traumatic Growth Inventory (PTGI) were used to evaluate patients' psychological resilience, cognitive flexibility, and PTG levels. Statistical methods included the independent sample t test, Pearson analysis, and linear regression analysis.
Results:
The total scores of CDRISC, cognitive flexibility scale and PTGI in 205 patients was (42.98 ± 6.13), (95.04 ± 17.98) and (49.77 ± 9.92), respectively. There was a significant positive correlation between psychological resilience, cognitive flexibility, and PTG levels in patients with severe sepsis treated with CRRT (p < 0.05). Psychological resilience and cognitive flexibility had positive predictive effects on PTG, and there were significant positive predictive effects between psychological resilience and cognitive flexibility (p < 0.05). Psychological resilience directly and positively predicted PTG (β = 0.538, p < 0.05). The indirect effect of psychological resilience on cognitive flexibility was significant (β = 0.677, p < 0.05), and the indirect effect of cognitive flexibility on PTG was significant (β = 0.165, p < 0.05). The chain-mediating effect between psychological resilience, cognitive flexibility, and PTG was significant (β = 0.112, p < 0.05).
Conclusion:
Psychological resilience can affect the PTG level of patients with severe sepsis treated with CRRT and can also indirectly affect PTG levels through direct chain mediation of cognitive flexibility. Targeted intervention strategies should be formulated to improve mental health and promote clinical prognosis.
Related Concept Videos
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Introduction to Stress and Lifestyle
Psychodynamic Therapy
Stress Prevention and Stress Management Techniques VI
Motivation and Self-Determination
Motivation, the driving force behind behavior, plays a pivotal role at every stage of the change process. The research...
Cognitive Development During Adulthood
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...

