Rapidly progressive dementia due to superior sagittal sinus dural arteriovenous fistula: A case report

Hiroki Karita1,2, Koji Hirata1, Kyoji Tsuda1

  • 1Department of Neurosurgery Ibaraki Seinan Medical Center Hospital Ibaraki Japan.

PubMed
Abstract

Insights

Dural arteriovenous fistula (dAVF) can cause memory loss. Early diagnosis and surgical treatment of dAVF significantly improve cognitive function and neurological symptoms.

Area of Science:

  • Neurology
  • Neurosurgery
  • Vascular Neurology

Background:

  • Dural arteriovenous fistulas (dAVF) are rare causes of cognitive decline.
  • Memory disturbance as a primary symptom of dAVF can lead to delayed diagnosis.

Purpose of the Study:

  • To highlight the importance of considering dAVF in patients with memory disturbance.
  • To present a case of successful treatment of dAVF presenting with cognitive decline.

Main Methods:

  • Case report of a 74-year-old male with progressive cognitive decline.
  • Magnetic resonance imaging (MRI) and angiography for dAVF diagnosis.
  • Surgical disconnection of superior sagittal sinus dAVF.

Main Results:

  • The patient presented with cognitive decline, gait disturbance, dysarthria, and ataxia.
  • Angiography confirmed a superior sagittal sinus dAVF.
  • Post-surgical treatment led to significant improvement in cognitive function and neurological deficits.

Conclusions:

  • Dural arteriovenous fistula should be considered in the differential diagnosis of memory disturbance.
  • Prompt diagnosis and appropriate treatment of dAVF can lead to symptom resolution.
  • Successful surgical intervention resulted in a modified Rankin Scale score of 2.

Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
41
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
48
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
31
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
43
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
31
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
35