Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leveraging nanoparticle protein corona to advance plasma proteome profiling.

Nature communications·2026
Same author

A minimally invasive, scalable and reproducible neonatal rat model of severe focal brain injury.

Brain communications·2026
Same author

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes.

Nature communications·2026
Same author

Melt Electrowriting High Resolution Poly(ethylene-co-vinyl acetate) Scaffolds for Soft Tissue Engineering.

Advanced healthcare materials·2026
Same author

Chronic intestinal immune activation reveals separable impacts of inflammation and barrier loss on hallmarks of ageing.

PloS one·2026
Same author

Renovating Neural Networks With Viral-Mediated Gene Transfer From A Tissue Contacting Matrix Mimic.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Menopause and Its Implications for Stroke in Women.

Stroke·2026
Same journal

Physician Approaches to Determining Goals of Stroke Care for Patients Living With Disability or Dementia: Results from the SEED Mixed-Methods Study.

Stroke·2026
Same journal

Aspirin for Stroke Primary Prevention: A Step Toward Genetic-Driven Personalized Medicine.

Stroke·2026
Same journal

Cognition After Stroke: It Is a Long Story.

Stroke·2026
Same journal

Emerging Therapy Critique: Glibenclamide for Cerebral Edema-A Semi-CHARMed Treatment.

Stroke·2026
Same journal

Health Care-Seeking Behavior Patterns Among Immigrant Populations.

Stroke·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
07:56

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

Published on: April 21, 2017

10.5K

Innovative Hydrogel-Based Treatments for Neonatal Stroke.

Victor Mondal1, Emily Ross-Munro1, Kate Firipis2,3,4

  • 1School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia (V.M., E.R.-M., G.K.B., R.K., M.M.H., D.W.W., M.T., B.F.).

Stroke
|May 22, 2025
PubMed
Summary
This summary is machine-generated.

Neonatal stroke, a serious condition affecting newborns, currently lacks effective treatments for brain damage. This review explores how advanced hydrogel therapies show promise for repairing brain injuries in infants after stroke.

Keywords:
brain injurieshydrogelinfant healthinfant, newborn, diseasesregenerationstroketranslational science, biomedical

More Related Videos

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke
09:41

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke

Published on: October 1, 2020

5.0K
Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
07:57

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin

Published on: August 25, 2022

2.8K

Related Experiment Videos

Last Updated: Jun 18, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
07:56

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

Published on: April 21, 2017

10.5K
Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke
09:41

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke

Published on: October 1, 2020

5.0K
Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
07:57

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin

Published on: August 25, 2022

2.8K

Area of Science:

  • Biomaterials Science
  • Neuroscience
  • Regenerative Medicine

Background:

  • Neonatal stroke affects over 1 in 2500 newborns, leading to severe disabilities like cerebral palsy and epilepsy.
  • The risk of stroke in newborns is notably high, with significant long-term clinical and socioeconomic consequences.
  • Current medical interventions do not offer treatments for the brain damage caused by neonatal stroke.

Purpose of the Study:

  • To review the potential of biocompatible hydrogels in addressing neonatal stroke pathophysiology.
  • To explore the application of hydrogel therapies for repairing brain damage in neonatal stroke.
  • To provide a comprehensive perspective on hydrogel therapy for improving outcomes in infants with severe brain injury.

Main Methods:

  • Synthesis of current knowledge on biocompatible hydrogels.
  • Analysis of hydrogel properties relevant to tissue repair (tunable elasticity, stiffness, shear-thinning).
  • Review of hydrogel applications in central nervous system lesion repair.

Main Results:

  • Hydrogels offer tunable properties for controlled local delivery of therapeutic agents.
  • Engineered hydrogels can potentially address the specific pathophysiology of neonatal stroke.
  • Hydrogels have demonstrated efficacy in repairing severe focal lesions in the adult central nervous system.

Conclusions:

  • Biocompatible hydrogels represent a promising therapeutic strategy for neonatal stroke.
  • Hydrogel therapy holds potential for improving functional outcomes in infants with brain injury.
  • Further research into cutting-edge hydrogel therapies is crucial for clinical translation.