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Cancer-Related Pain Management in Pregnancy-A Review.

Zainab Yusufali Motiwala1, Shahzad Raza2, Lucas Y Fernet3

  • 1JNMCH, Aligarh Muslim University, Aligarh, India.

Journal of Palliative Medicine
|May 22, 2025
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Summary
This summary is machine-generated.

Managing cancer pain in pregnant patients requires balancing maternal pain relief and fetal safety. This review explores safe pharmacological and interventional strategies, addressing care disparities for improved outcomes.

Keywords:
cancer-related paininterventional techniquesminority populationspain management disparitiespharmacological agents

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Area of Science:

  • Oncology
  • Pain Management
  • Maternal-Fetal Medicine

Background:

  • Cancer pain in pregnancy presents unique challenges due to the need for maternal analgesia and fetal safety.
  • Individualized treatment is crucial, considering pain pathophysiology, maternal-fetal safety, and pharmacokinetics.

Purpose of the Study:

  • To review safe and effective pharmacological and interventional strategies for cancer pain in pregnant patients.
  • To highlight disparities in access to care for this population.

Main Methods:

  • A comprehensive literature review of 4766 articles, with 98 studies included for analysis.
  • Included studies focused on pregnant individuals with various malignancies, categorizing pain types and treatment options.

Main Results:

  • Recommended analgesics include acetaminophen, opioids, and certain neuropathic medications; NSAIDs require extreme caution. Ultrasound-guided interventional methods are preferred over radiation-guided procedures.
  • Diverse populations face significant barriers to adequate pain control, indicating disparities in care access.

Conclusions:

  • Optimal cancer pain management in pregnancy requires a multidisciplinary, individualized approach.
  • Enhancing clinical evidence and ensuring culturally competent care are critical for improving patient outcomes.