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Analysis of strategies China should adopt in response to global pertussis trends

Shuying Jiang1, Chunyan Wu2, Zhenhua Zhu3

  • 1Department of Pharmacy, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.

Human Vaccines & Immunotherapeutics
|May 22, 2025
PubMed

Insights

Pertussis (whooping cough) is resurging globally, particularly post-COVID-19, with rising cases in all age groups. Current pertussis vaccination strategies show gaps, necessitating improved vaccine development and public health interventions.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Vaccinology

Background:

  • Pertussis (whooping cough) incidence has increased globally in recent years.
  • A significant resurgence of pertussis has been observed, particularly following the COVID-19 pandemic.
  • While infants are most affected, pertussis incidence has notably risen among adolescents and adults.

Purpose of the Study:

  • To highlight the increasing incidence of pertussis across various age groups.
  • To identify deficiencies in current pertussis vaccination guidelines.
  • To emphasize the need for enhanced research, immunization, monitoring, and public awareness.

Main Methods:

  • Review of recent pertussis incidence data.
  • Analysis of current pertussis vaccination guidelines and coverage.
  • Assessment of disease trends in infants, adolescents, and adults.

Main Results:

  • Reported pertussis incidence is increasing worldwide.
  • Significant rise in pertussis cases observed in adolescents and adults.
  • Current vaccination strategies reveal gaps in coverage for key demographics.

Conclusions:

  • There is an urgent need to address pertussis resurgence through improved vaccination strategies.
  • Enhanced research and development of new pertussis vaccines are critical.
  • Strengthening immunization programs, monitoring, and public awareness is essential to control pertussis spread.

Keywords:
pertussisvaccinationvaccine

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