Related Experiment Video

Updated: May 23, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.0K

Epidemiological characteristics of six common respiratory pathogen infections in children

Zheng Tang1,2, Huihui Fan3, Yaling Tian3

  • 1Department of Transfusion Medicine, The Central Hospital of Yongzhou, Yongzhou, China.

Microbiology Spectrum
|May 22, 2025
PubMed

Insights

This study found that human rhinovirus (HRV) was the most common respiratory pathogen in children, with significant age and seasonal variations observed for influenza A (FluA), influenza B (FluB), and Mycoplasma pneumoniae (MP). Findings aid in targeted prevention and treatment strategies for pediatric respiratory infections.

Area of Science:

  • Pediatric infectious diseases
  • Respiratory virology and bacteriology
  • Public health epidemiology

Background:

  • Respiratory infections are a major cause of childhood illness and mortality globally.
  • Current diagnostic methods often lack the speed and accuracy for timely clinical intervention.
  • Understanding pathogen prevalence by age and season is crucial for effective control.

Purpose of the Study:

  • To analyze the epidemiological characteristics of common respiratory pathogens in pediatric patients.
  • To identify age-specific and seasonal variations in the incidence of six key respiratory pathogens.
  • To inform targeted prevention and treatment strategies for childhood respiratory infections.

Main Methods:

  • Retrospective analysis of 15,397 pediatric respiratory pathogen test results.
  • Data collected from Yongzhou Central Hospital between June 2023 and May 2024.
  • Evaluation of pathogen detection rates across different age groups and seasons.

Main Results:

  • Overall pathogen positivity rate was 77.0%, with human rhinovirus (HRV) being most prevalent (32.4%).
  • Influenza A (FluA), influenza B (FluB), and Mycoplasma pneumoniae (MP) infections increased with age, peaking in school-aged children.
  • Respiratory syncytial virus (RSV) was highest in infants, adenovirus (ADV) in preschoolers, and MP surged in summer.

Conclusions:

  • Pediatric respiratory pathogen incidence is significantly influenced by age and season.
  • Targeted interventions, including health education and timely diagnosis, are essential based on pathogen-specific trends.
  • This regional data supports improved management and control of pediatric respiratory infections.

Keywords:
Mycoplasma pneumoniaeacute respiratory infectionadenoviruschildrenhuman rhinovirusinfluenzarespiratory syncytial virus

More Related Videos

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

7.9K
Assessing Respiratory Immune Responses to Haemophilus Influenzae06:32

Assessing Respiratory Immune Responses to Haemophilus Influenzae

Published on: June 29, 2021

2.0K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
201
Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
201
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
197
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
790
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
340
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.3K