Related Experiment Video
Updated: May 23, 2025

In Vivo Functional Assessment of Rat Masseter Muscle Following Surgical Creation of a Volumetric Muscle Loss (VML) Injury
Published on: November 15, 2024
The Jaw-Locking Case of a Missed Tetanus Booster
Erica Westlake1, Katherine Billings2, Ann McMoran1
1Cooper University Hospital, Department of Emergency Medicine, Camden, New Jersey.
Introduction:
Tetanus is a now rare disease due to the widespread administration of scheduled and prophylactic vaccines, making it exceptionally uncommon to appear in many emergency departments. Clinical suspicion alone is used to make the diagnosis as there are currently no immediately available diagnostic tests available to the clinician. If left unrecognized and untreated, however, tetanus can lead to airway compromise and death.
Case Report:
We report a case of a young male who presented to the emergency department with intermittent full body spasms and stiffness of the masseter muscles in the setting of recent assaults and lacerations weeks prior who had not received tetanus since 2008. Immediate calls were placed to infectious disease consultants and the patient was treated with intravenous immunoglobulin, tetanus immunization, metronidazole, and ceftriaxone. Further work up revealed rhabdomyolysis, elevated lactate, and unremarkable imaging.
Conclusion:
Following treatment, the patient's symptoms improved to resolution with completion of therapy, effectively confirming the diagnosis of tetanus.
Related Concept Videos
Muscle Stimulation Frequency
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Vaccinations
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax-II
Clinical Manifestations:

