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Updated: Jan 18, 2026

Cell Type-specific Gene Expression Profiling in the Mouse Liver
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HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury

Wei-Chien Yuan1, Andrew S Earl2, Sai Ma3

  • 1Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan; Cancer and Immunology Research Center, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.

Cell Stem Cell
|May 22, 2025
PubMed

Keywords:
HBO1Hippo-YAPepigenetic regulationhepatocyte reprogrammingin vivo CRISPR screen

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