Related Experiment Video
Updated: Sep 25, 2026

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
Published on: May 22, 2018
A survey of sequence-to-graph mapping algorithms in the pangenome era
Yingbo Cui1, Chenchen Peng2, Zeyu Xia2
1College of Computer Science and Technology, National University of Defense Technology, No.137 Yanwachi St, 410073, Changsha, People's Republic of China. yingbocui@nudt.edu.cn.
Abstract:
A pangenome can reveal the genetic diversity across different individuals simultaneously. It offers a more comprehensive reference for genome analysis compared to a single linear genome that may introduce allele bias. Pangenomes are often represented as genome graphs, making sequence-to-graph mapping a fundamental task for pangenome construction and analysis. Numerous sequence-to-graph mapping algorithms have been developed over the past few years. Here, we provide a review of the advancements in sequence-to-graph mapping algorithms in the pangenome era. We also discuss the challenges and opportunities that arise in the context of pangenome graphs.
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Genomics
Modern Molecular Taxonomy
Genome Annotation and Assembly
Maxam-Gilbert Sequencing
Challenges of the Maxam-Gilbert Method
The...
Next-generation Sequencing
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

