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Updated: Jan 18, 2026
Determining Bile Duct Density in the Mouse Liver
Published on: April 30, 2019
Ultrasound Findings of Bile Duct Involvement in Pediatric Langerhans Cell Histiocytosis
Jiachao Wang1, Xin Wei1, Yu Wang1
1Department of Ultrasound, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Objective:
This study aimed to analyze the ultrasound findings of bile duct involvement in pediatric Langerhans cell histiocytosis (LCH).
Methods:
We retrospectively analyzed 42 patients diagnosed with pediatric LCH by pathology at our hospital from December 2016 to December 2023. All patients had comprehensive clinical data and ultrasound findings indicating biliary abnormalities. This study analyzed intrahepatic and extrahepatic bile duct dilation, the extent of bile duct wall thickening, and surrounding abnormal echoes.
Results:
Among the 42 children, ultrasonography showed intrahepatic and extrahepatic bile duct dilation in 27 cases (64%), bile duct wall thickening in 21 cases (50%), hypoechoic areas along the intrahepatic bile ducts in 16 cases (38%), and thickening of the Glisson's capsule with decreased echogenicity around the bile ducts in 8 cases (19%).
Conclusion:
Ultrasonography revealing varying degrees of bile duct dilatation or stenosis, thickened bile duct walls, and abnormal echo patterns along the bile duct in the liver in pediatric patients with cholangitis should raise suspicion for LCH.
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