Intrauterine twin demise and oligomeganephronia

Oligomeganephronia, characterized clinically be early renal failure and histologically by large, sparse glomeruli, is of undetermined etiology. This is the first documented report of an intrauterine fetal demise of one twin in association with oligomeganephronia in the other, and suggests that these two conditions may be related etiologically. The suggested mechanism is a renal vascular insult, late in the pregnancy, as the precipitating event.