Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Documentation in Long-Term and Home Healthcare Setting01:29

Documentation in Long-Term and Home Healthcare Setting

996
Documentation in long-term care facilities and home healthcare settings is crucial for ensuring continuous, coordinated, and comprehensive care for patients. Each setting has its specific documentation processes and tools:
Long-Term Care Facilities
996
Secondary Healthcare System01:11

Secondary Healthcare System

1.6K
Secondary healthcare is offered by a specialist, generally in hospitals or clinics for patients referred by primary healthcare providers. It occurs when a person has an illness or injury that requires specific medical care. Secondary care is often referred to as acute care. Secondary care can range from uncomplicated care to repair a minor laceration or treat a strep throat infection to more complicated emergent care, such as treating a head injury sustained in an automobile accident. Whatever...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Racial identity, marginalization, and depression in pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Application of the 2024 McDonald Criteria in Individuals With Nonspecific Symptoms or Incidental Imaging Findings in a Multicenter Study.

Neurology·2026
Same author

Impact of depression and anxiety on health-related quality of life changes over time within individuals with rheumatoid arthritis or inflammatory bowel disease: A prospective Canadian cohort study.

PloS one·2026
Same author

Prescription drug dispensations 15 years before multiple sclerosis onset: A matched cohort study, British Columbia, Canada.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Phenotyping healthcare use before pediatric-onset multiple sclerosis, including by sex and age: A matched cohort study.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Interventions to address social and structural conditions for individuals with select complex, chronic, disabling conditions: a scoping review protocol.

JBI evidence synthesis·2026

Related Experiment Video

Updated: Sep 20, 2025

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

16.0K

Health care use preceding pediatric multiple sclerosis: A population-based study from Ontario, Canada.

Ruth Ann Marrie1, Colleen J Maxwell2,3, Karl Everett3

  • 1Departments of Medicine and Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada Department of Medicine, Nova Scotia Health, Halifax, NS, Canada.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|May 23, 2025
PubMed
Summary

Pediatric multiple sclerosis (MS) patients use more healthcare services from birth, suggesting a potential prodromal phase up to six years before diagnosis. Early life may be a critical risk period for MS development.

Keywords:
Multiple sclerosisadministrative datahealth care usepediatric

More Related Videos

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.2K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.4K

Related Experiment Videos

Last Updated: Sep 20, 2025

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

16.0K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.2K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.4K

Area of Science:

  • Neurology
  • Pediatric Health
  • Epidemiology

Background:

  • Previous multiple sclerosis (MS) prodrome research primarily focused on adults.
  • Understanding early health care utilization in pediatric MS is crucial for early detection.

Purpose of the Study:

  • To compare health care use rates and reasons in youth with and without MS.
  • To analyze health care utilization relative to the MS index date and birth.

Main Methods:

  • Retrospective cohort study using Canadian population-based administrative data (1991-2020).
  • Matched youth (<18 years) with pediatric-onset MS to controls (up to 5:1 ratio).
  • Compared health services use, adjusting for demographic and socioeconomic factors.

Main Results:

  • Individuals with pediatric MS showed higher physician services use and hospitalizations starting six years before the MS index date.
  • Elevated physician visit rates in the MS cohort were observed in early life, increasing as the diagnosis approached.
  • Findings were consistent across full cohorts and subcohorts analyzed from birth.

Conclusions:

  • Youth with pediatric-onset MS demonstrate increased health care utilization from birth.
  • Early life represents a potential risk period for MS development.
  • A prodromal phase for MS may begin as early as six years prior to symptom onset.