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Related Experiment Videos

Human conditioned compensatory response to alcohol cues: initial evidence.

D B Newlin

    Alcohol (Fayetteville, N.Y.)
    |May 1, 1985
    PubMed
    Summary

    Alcohol cues trigger body responses opposite to alcohol's effects. This suggests classical conditioning may play a role in human alcohol problems, influencing autonomic responses like pulse and temperature.

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    Area of Science:

    • Psychology
    • Neuroscience
    • Human Physiology

    Background:

    • Alcohol consumption is a significant public health concern.
    • Understanding the physiological and psychological mechanisms underlying alcohol use is crucial.
    • Classical conditioning principles have been explored in relation to substance use disorders.

    Purpose of the Study:

    • To investigate whether alcohol-related cues can elicit conditioned autonomic responses in humans.
    • To determine if these conditioned responses are compensatory to the pharmacological effects of alcohol.
    • To support the application of a classical conditioning model to human alcohol problems.

    Main Methods:

    • A pilot study involving normal male social drinkers.
    • Four sessions of alcohol (or placebo) conditioning.
    • Administration of a placebo following conditioning sessions.
    • Measurement of autonomic responses including pulse transit time, vasomotor activity, and finger temperature.

    Main Results:

    • Alcohol cues elicited conditioned autonomic responses.
    • These responses were opposite in direction to the known effects of alcohol.
    • Observed compensatory responses included decreased pulse transit time, vasomotor activity, and finger temperature.

    Conclusions:

    • The findings support the hypothesis that classical conditioning can influence autonomic responses to alcohol cues.
    • This research provides preliminary evidence for the utility of a classical conditioning model in understanding human alcohol problems.
    • Conditioned physiological responses may contribute to the maintenance or relapse of alcohol use behaviors.

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