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Prevalence of Vitamin D Deficiency in Children and the Relationship of Vitamin D Levels With Allergic and
Insights
Vitamin D deficiency is common in children, especially girls and adolescents. Risk factors include female sex, adolescence, and spring season, with lower levels seen in obese and rheumatic disease groups.
Area of Science:
- Pediatrics
- Endocrinology
- Nutritional Science
Background:
- Vitamin D deficiency is a growing concern in pediatric populations.
- Understanding prevalence and risk factors is crucial for public health initiatives.
Purpose of the Study:
- Determine the prevalence of vitamin D deficiency in children.
- Compare vitamin D levels between healthy children and those with various health conditions.
Main Methods:
- Retrospective analysis of 3,532 children's vitamin D levels (25-OH vitamin D).
- Data collected between June 2022 and June 2023.
- Analysis by age, sex, season, reason for admission, and diagnosis.
Main Results:
- Mean vitamin D level was 23 ± 12.5 ng/mL; 28.4% insufficient, 18.2% deficient.
- Highest risk factors for deficiency: female sex, adolescent age, spring season (p < .000).
- Lowest vitamin D levels observed in children with obesity (16.1 ng/mL) and rheumatic diseases (18.1 ng/mL).
Conclusions:
- Vitamin D deficiency is prevalent in children, with significant risk factors identified.
- Targeted screening may be beneficial for children with allergies, rheumatic diseases, or recurrent infections.
- Consider extending vitamin D prophylaxis to obese children and adolescents.
Introduction:
This study aimed to determine the prevalence of vitamin D deficiency in children and compare vitamin D levels between healthy children and children with various health problems, including allergic, rheumatic and infectious diseases.
Method:
Children who were admitted to our center for any reason between June 2022 and June 2023 and had a vitamin D level check were included in the study. Vitamin D levels were examined by age, sex, season, reason for admission and final diagnosis.
Results:
The mean 25-OH vitamin D level of 3,532 children was 23 ± 12.5 ng/mL. It was insufficient in 28.4% of the cases and deficient in 18.2%. Factors associated with the highest risk of vitamin D deficiency were female sex, adolescent age, and spring season (p < .000). By diagnostic group, the mean vitamin D level in healthy children was 22.0 ng/mL. The groups with the lowest vitamin D levels were obesity (16.1 ng/mL) and rheumatic disease (18.1 ng/mL).
Discussion:
This study showed that vitamin D deficiency is quite common in children, and the most important risk factors are female gender, adolescent age group and winter-spring season. Although routine vitamin D screening is not recommended, testing may be performed in children with a history of allergies, rheumatic diseases, or frequent infections. It may be recommended to extend vitamin D prophylaxis to obese individuals and adolescents.
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