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Diabetic Retinopathy

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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Related Experiment Video

Updated: May 7, 2026

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Retinal angiomatous proliferation and pachychoroid.

J L Sánchez-Vicente¹, E M Gámez-Jiménez¹, J C Fernández-Fontán¹

¹Servicio de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, Spain.

Archivos De La Sociedad Espanola De Oftalmologia

|May 23, 2025

Summary

Retinal angiomatous proliferation (RAP), a type 3 choroidal neovascular membrane (CNV), is rarely associated with pachychoroidopathy. This case report explores this rare association and its potential ischemic cause.

Keywords:

Choroidal neovascular membrane Membrana neovascular coroidea Pachychoroidopathy Paquicoroidopatía Proliferación angiomatosa retiniana Retinal angiomatous proliferation

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Last Updated: May 7, 2026

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

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Published on: March 12, 2022

Area of Science:

Ophthalmology
Retinal Diseases
Choroidal Neovascularization

Background:

Pachychoroidopathy is characterized by a thickened choroid with dilated choroidal vessels (pachyvessels).
Retinal angiomatous proliferation (RAP), also known as type 3 choroidal neovascularization (CNV), involves neovascularization originating from the retinal pigment epithelium or choroid.

Observation:

The association between pachychoroidopathy and RAP/type 3 CNV is infrequently documented.
A case of RAP occurring in the context of pachychoroidopathy is presented.

Findings:

The proposed mechanism for RAP in pachychoroidopathy involves ischemia.
This ischemia is hypothesized to result from choriocapillaris loss due to compression of pachyvessels.

Implications:

Understanding this association may refine diagnostic criteria for pachychoroid spectrum disorders.
Further research is warranted to elucidate the pathophysiology and clinical significance of RAP in pachychoroidopathy.