Nutraceutical approaches for Autism Spectrum Disorder treatment

Area of Science:

• Neuroscience
• Immunology
• Genetics

Background:

• Autism Spectrum Disorder (ASD) is a growing neurodevelopmental condition affecting social interaction, communication, and sensory responses.
• Prevalence is 1 in 100 children, influenced by genetic and environmental factors.
• Neuroinflammation, marked by microglial cell activation, is a key feature of ASD.

Purpose of the Study:

• To review antioxidant and anti-inflammatory compounds for potential use in managing ASD.
• To highlight molecules successful in preclinical and clinical trials for ASD-related neuroinflammation.
• To explore potential therapeutic strategies targeting neuroinflammation in ASD.

Main Methods:

• Literature review of preclinical and clinical studies on nutraceuticals for ASD.
• Analysis of molecules demonstrating efficacy in attenuating neuroinflammation.
• Identification of potential therapeutic associations for future research.

Main Results:

• Several antioxidant and anti-inflammatory compounds have shown promise in preclinical and clinical trials.
• These compounds may help mitigate the effects of neuroinflammation in individuals with ASD.
• Specific molecules and their mechanisms warrant further investigation.

Conclusions:

• Nutraceutical supplements with antioxidant and anti-inflammatory properties are promising for ASD management.
• Targeting neuroinflammation represents a potential therapeutic avenue for ASD.
• Further research into specific molecules and their associations is recommended.