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Right Ventricular Function and Afterload Following Novel Transcatheter Tricuspid Valve Replacement.
Hannah Kempton1, Mayooran Namasivayam2, Thomas Meredith2
1Department of Cardiology, St Vincent's Hospital, Sydney, New South Wales, Australia; Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
JACC. Case Reports
|May 23, 2025
Summary
Assessing right ventricular (RV) function is crucial but challenging with tricuspid regurgitation (TR). This study explores alternative methods for measuring RV systolic function in severe TR patients undergoing novel transcatheter tricuspid valve intervention.
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomedical Engineering
Background:
- Right ventricular (RV) function is a key prognostic indicator in pulmonary hypertension and valvular heart disease.
- Accurate assessment of RV function is often limited by the presence of tricuspid regurgitation (TR).
Observation:
- A novel transcatheter tricuspid valve device was implanted in a patient with severe TR.
- The study highlights limitations in current methods for assessing RV systolic function in this context.
Findings:
- The case demonstrates the need for alternative methods to measure RV systolic function, considering pulmonary pressure in severe TR.
- Perforation of the prosthesis's pop-off zone to create mild residual TR can reduce RV afterload and its impact on RV systolic function.
Implications:
- This approach offers a potential strategy to improve RV systolic function assessment and management in patients with severe TR.
- It underscores the clinical utility of device modifications for optimizing outcomes in transcatheter tricuspid valve interventions.
