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Updated: Sep 20, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Pharmacological interactions between antihypertensive regimens and drugs prescribed in the emergency department
Luque Esparza Lilia Edith1, Marco Antonio Osorio García2, Dealmy Delgadillo Guzmán3
1Department of Anesthesiology, General Hospital of Zone No.51, Mexican Social Security Institute, Gómez Palacio, Durango, Mexico.
Abstract:
The risk of drug interactions in patients with HTN is aggravated when prescribing treatments for additional acute pathologies. This can favor adverse reactions to medications or make it difficult to control blood pressure during their stay in the emergency room.
Objective:
Identify and classify, using CDSS, the IFFs between the antihypertensive treatment regimen and the drugs prescribed in the emergency department.
Material And Methods:
Fifty-three patients with systemic arterial hypertension were treated in the emergency department. Clinical decision support systems are used to identify and classify potential FFs.
Results:
IFFs were found in 96.2% of hypertensive patients in the emergency department. Those with the highest frequency were of moderate risk. The most frequent mechanism was pharmacodynamic, mainly synergistic by ad-dition.
Conclusions:
The correlation index between the number of drugs prescribed in the emer-gency room and the presence of IFF shows the need to carry out a scrutiny of the joint pharmaco-logical behavior used in hypertensive patients who attend emergency medical care to rationalize the use of medications reducing the probability of presenting IFF.
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