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Updated: Aug 10, 2026

Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Heat delivery accompanying pulsed field ablation
Angiolo Farina1, Antonio Fasano2, Massimo Grimaldi3
1Dipartimento di Matematica e Informatica "Ulisse Dini", Viale Morgagni 67/a, Firenze, 50134, Italy.
Abstract:
Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient's luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.
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