A radiological review of male nipple discharge

Male nipple discharge is uncommon and highly associated with malignancy. However, it can also be due to benign processes. In addition to physical examination, all patients should undergo a radiological examination with mammography and/or ultrasound. Furthermore, we propose the use of contrast-enhanced mammography (CEM) in cases of suspicious nipple discharge due to the high negative predictive value of this technique, potentially reducing the number of unnecessary biopsies. The aim of this article is to review the imaging findings of the most common causes of male nipple discharge, both benign and malignant. Additionally, we would like to share our experience with the use of CEM in studying this condition.