Prolonged Bacillus cereus bacteremia: case report and literature review

A 77-year-old man, initially diagnosed with pneumonia presented with fever and was administered continuous amino acid preparations and meropenem. Bacillus cereus was isolated from two separate sets of blood cultures, leading to a diagnosis of catheter-related bloodstream infection. Despite treatment with teicoplanin (TEIC) and additional antibiotics, B. cereus was continuously yielded from blood cultures for approximately four weeks. Ultimately, the patient was successfully treated with a combination of TEIC and clindamycin for six weeks, along with gentamicin for two weeks. This case report further reviews 17 cases of persistent B. cereus bacteremia. These cases provide valuable insights into the management of challenging cases of B. cereus bacteremia.