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Reference datasets for commissioning of model-based dose calculation algorithms for electronic brachytherapy.

Iymad R Mansour1,2,3, Christian Valdes-Cortez4, David Santiago Ayala Alvarez5

  • 1Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University, Ottawa, Canada.

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Summary
This summary is machine-generated.

This study introduces two clinical test cases for electronic brachytherapy (eBT) model-based dose calculation algorithms (MBDCAs) for skin irradiation. The validated dataset aids researchers in commissioning eBT systems and improving dosimetric calculations.

Keywords:
Monte Carlo (MC)intraoperative radiation therapy (IORT)model based dose calculation algorithms (MBDCA)

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Dosimetry

Background:

  • Electronic brachytherapy (eBT) offers precise skin irradiation.
  • Commissioning model-based dose calculation algorithms (MBDCAs) requires robust clinical test cases.
  • Surface applicators present unique dosimetric challenges.

Purpose of the Study:

  • To present the first two clinical test cases for commissioning eBT MBDCAs for skin irradiation.
  • To validate dose calculations for surface applicator eBT in uniform and heterogeneous phantoms.
  • To provide a comprehensive dataset for algorithm evaluation.

Main Methods:

  • Utilized the INTRABEAM 30 mm surface applicator for two test cases.
  • Evaluated performance in a water phantom (uniform) and a layered phantom (heterogeneous).
  • Compared Radiance treatment planning system (TPS) Monte Carlo (MC) calculations with independent EGSnrc and PENELOPE simulations.

Main Results:

  • Dose-to-medium calculations from the TPS showed agreement with independent MC simulations.
  • Results were within expected Type A and B statistical uncertainties.
  • Validated the accuracy of MBDCAs for surface eBT applications.

Conclusions:

  • The provided dataset is a valuable resource for commissioning eBT MBDCAs.
  • It facilitates the development of clinical test cases for other eBT systems.
  • Serves as an educational tool and benchmark for low-energy domain dosimetric calculations.