Related Experiment Video

Updated: Oct 2, 2026

Patch-clamp Capacitance Measurements and Ca2+ Imaging at Single Nerve Terminals in Retinal Slices
09:16

Patch-clamp Capacitance Measurements and Ca2+ Imaging at Single Nerve Terminals in Retinal Slices

Published on: January 19, 2012

Capacitative transients in voltage-clamped epithelia

J F Garcia-Diaz, A Essig

    Biophysical Journal
    |September 1, 1985
    PubMed

    More Related Videos

    The Xenopus Oocyte Cut-open Vaseline Gap Voltage-clamp Technique With Fluorometry10:57

    The Xenopus Oocyte Cut-open Vaseline Gap Voltage-clamp Technique With Fluorometry

    Published on: March 11, 2014

    Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies11:42

    Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies

    Published on: January 22, 2015

    Related Concept Videos

    Patch Clamp01:18

    Patch Clamp

    Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
    In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
    Voltage-gated Ion Channels01:26

    Voltage-gated Ion Channels

    Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
    Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several types of...
    Capacitor in an AC Circuit01:23

    Capacitor in an AC Circuit

    A capacitor is charged by passing an electric current through it, which causes the plates to start accumulating an electrostatic charge. Since the strength of the charging current is maximum when the capacitor plates are uncharged and gradually decreases exponentially until the capacitor is fully charged, the charging process is neither instantaneous nor linear. The property of a capacitor to store a charge on its plates is called its capacitance.
    Consider a purely capacitive circuit consisting...
    Action Potential: Phases of Stimulation01:28

    Action Potential: Phases of Stimulation

    The action potential is a complex electrical event that occurs in excitable cells, such as neurons and muscle cells. It consists of several distinct phases, each with specific characteristics.
    Resting Phase:
    In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...
    Voltage-gated Ion Channels01:26

    Voltage-gated Ion Channels

    Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
    Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several types of...
    MOS Capacitor01:25

    MOS Capacitor

    A Metal-Oxide-Semiconductor (MOS) capacitor is a fundamental structure used extensively in semiconductor device technology, particularly in the fabrication of integrated circuits and MOSFETs (metal-oxide-semiconductor field-effect transistors). The MOS capacitor consists of three layers: a metal gate, a dielectric oxide, and a semiconductor substrate.
    The metal gate is typically made from highly conductive materials such as aluminum or polysilicon. Beneath the metal gate lies a thin layer of...