Robot-assisted vs open kidney transplantation from deceased donors

Luca Afferi1,2,3, Angelo Territo2, Alessio Pecoraro4,5

  • 1Department of Surgery, Autonomous University of Barcelona, Barcelona, Spain.

BJU International
|May 26, 2025
PubMed
Abstract

Insights

Robot-assisted kidney transplantation (RAKT) shows faster anastomosis and rewarming times compared to open kidney transplantation (OKT) in deceased donor recipients. Both approaches demonstrate similar long-term survival and complication rates.

Area of Science:

  • Nephrology
  • Surgical Innovation
  • Transplantation Medicine

Background:

  • Kidney transplantation is a vital treatment for end-stage renal disease.
  • Surgical approach selection, robot-assisted kidney transplantation (RAKT) versus open kidney transplantation (OKT), may influence patient outcomes.
  • Deceased donor kidney transplantation remains a critical area for surgical outcome optimization.

Purpose of the Study:

  • To compare intra-operative and postoperative surgical outcomes between RAKT and OKT in deceased donor kidney recipients.
  • To evaluate the impact of surgical approach on patient survival and complication rates.
  • To determine if RAKT offers advantages over OKT in specific surgical metrics.

Main Methods:

  • A multicentre retrospective cohort study involving 676 patients from 2015-2023 across seven European academic centres.
  • Propensity-score matching was used to balance baseline patient characteristics between RAKT and OKT groups.
  • Outcomes including intra- and postoperative complications (Clavien-Dindo), and survival endpoints (DFS, GS, RFS, OS) were analyzed using Kaplan-Meier estimates and log-rank tests.

Main Results:

  • After matching, 72 OKT and 37 RAKT recipients were compared. RAKT demonstrated significantly shorter rewarming and vascular anastomosis times (arterial and venous).
  • Open kidney transplantation (OKT) was associated with a shorter overall surgical time.
  • Intra-operative complications were less frequent in the RAKT group (2.7% vs. 8.3% in OKT), though not statistically significant (P=0.4). No significant differences were observed in postoperative complications or survival rates (DFS, GS, RFS, OS).

Conclusions:

  • Robot-assisted kidney transplantation (RAKT) is confirmed as a safe approach for deceased donor kidney transplantation.
  • RAKT shows superiority in reducing rewarming and vascular anastomosis times, particularly beneficial for selected patients.
  • While RAKT offers specific intra-operative advantages, long-term outcomes and complication rates are comparable to open kidney transplantation (OKT).

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