Related Experiment Video
Updated: Sep 20, 2025

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Prevalence and predictors of chronic disease among rural and medically underserved populations using smokeless
Elaine Sang1,2, Susan Silva3, Sarah Grenon3
1New Courtland Center for Transitions and Health, School of Nursing, University of Pennsylvania, Philadelphia, PA, United States.
Introduction:
Smokeless tobacco (SLT) is significant public health problem in the U.S. and is associated with chronic diseases, which includes both physical and mental health conditions. Inequities in use exist as rural and other medically underserved populations use SLT more than that of the general population. Our study examined prevalence of chronic disease and identified associated risk factors among rural and medically underserved populations using smokeless tobacco.
Methods:
We conducted a cross-sectional analysis of baseline data (N = 532) from a clinical trial promoting SLT cessation among adults living in rural and/or medically underserved areas and examined the rates of eight chronic diseases: cancer, lung disease, heart disease, stroke, mental health conditions, diabetes, arthritis/orthopedic conditions, and hypertension. Multivariable logistic regression was used to identify risk factors for four of the most common chronic diseases among study participants.
Results:
Over 60% of our sample of rural and medically underserved adults who use SLT also have at least one chronic disease. The most common chronic diseases were hypertension (38%), arthritis/orthopedic (23%), mental health (21%), and diabetes (12%). Increasing age and poor/fair health were associated with having hypertension, arthritis/orthopedic conditions, and/or diabetes. In addition, drinking alcohol <5 days per week was associated with having diabetes. Meanwhile, greater nicotine dependence, marital status, and having stained teeth were associated with having a mental health condition.
Conclusions:
Findings may inform the development of SLT cessation interventions as part of broader chronic disease management programs and as part of secondary prevention to minimize tobacco related morbidity.
Related Concept Videos
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Statistical Methods for Analyzing Epidemiological Data
Stress Prevention and Stress Management Techniques IV
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Chronic Obstructive Pulmonary Disease-I: Introduction
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...

