A Self-Powered Bioelectronic Suture via Hybrid Laser Treatment

Appropriate suture tension is crucial for effective wound healing, as improper tension may lead to wound dehiscence or ischemia. Advances in bioelectronic sutures enable monitoring and therapy, but reliance on external power or complex circuits limits their use in long-term and minimally invasive applications. Herein, a self-powered bioelectronic suture (B-suture) is reported that enables real-time tension monitoring during suturing. The B-suture integrates a conductive composite within a capillary structure. Hybrid laser processing, combining continuous wave laser-induced phase separation and femtosecond laser-engraved microstructures, greatly enhances electro-mechanical properties and triboelectric sensing performance. The triboelectric nanogenerator-based principle enables tension detection in the 0-2 N range. In vitro and in vivo evaluations demonstrate biocompatibility and precise monitoring of suturing tightness. By providing real-time quantitative feedback, the proposed B-suture affords to improve wound closure quality, reduce postoperative complications, and advance bioelectronic applications in surgical practice.