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[Ectopic calcification of the knee joint]
Elina Hahn1, Iman Khalili2, Veit Krenn3
1Klinik für Orthopädie und Unfallchirurgie, Zentrum für Operative Rheumatologie, Krankenhaus Reinbek St. Adolfstift, Hamburger Str. 41, 21465, Reinbek, Deutschland. elina.hahn@krankenhaus-reinbek.de.
Zeitschrift Fur Rheumatologie
|May 26, 2025
Summary
A rare condition called tumoral calcinosis, a form of ectopic calcification, caused progressive swelling in an elderly man's knee. Diagnosis involved imaging, surgery, and lab tests revealing secondary hyperparathyroidism.
Area of Science:
- Orthopedics
- Nephrology
- Pathology
Background:
- Tumoral calcinosis is a rare condition characterized by calcium salt deposits.
- Ectopic calcification can manifest in various soft tissues.
- Infrapatellar swelling can mimic other joint pathologies.
Purpose of the Study:
- To present a case of tumoral calcinosis in the infrapatellar region.
- To highlight the diagnostic challenges and multidisciplinary approach required.
- To discuss the association with renal insufficiency and secondary hyperparathyroidism.
Main Methods:
- Clinical presentation of an 81-year-old male with knee swelling.
- Radiographic imaging to assess calcification patterns.
- Histopathological examination of resected tissue.
- Laboratory tests for renal function and parathyroid hormone levels.
Main Results:
- X-ray suggested bursal chondromatosis or ectopic calcification.
- Histopathology confirmed tumoral calcinosis.
- Laboratory findings indicated renal insufficiency and secondary hyperparathyroidism.
Conclusions:
- Tumoral calcinosis is a rare cause of infrapatellar swelling.
- A combination of imaging, histology, and biochemical analysis is crucial for diagnosis.
- The condition is associated with metabolic disturbances like secondary hyperparathyroidism.
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