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[Ectopic calcification of the knee joint].

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PubMed
Summary

A rare condition called tumoral calcinosis, a form of ectopic calcification, caused progressive swelling in an elderly man's knee. Diagnosis involved imaging, surgery, and lab tests revealing secondary hyperparathyroidism.

Keywords:
Dystrophic calcificationMetastatic calcificationSecondary hyperparathyroidismTeutschländer’s diseaseTumoral calcinosis

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Area of Science:

  • Orthopedics
  • Nephrology
  • Pathology

Background:

  • Tumoral calcinosis is a rare condition characterized by calcium salt deposits.
  • Ectopic calcification can manifest in various soft tissues.
  • Infrapatellar swelling can mimic other joint pathologies.

Purpose of the Study:

  • To present a case of tumoral calcinosis in the infrapatellar region.
  • To highlight the diagnostic challenges and multidisciplinary approach required.
  • To discuss the association with renal insufficiency and secondary hyperparathyroidism.

Main Methods:

  • Clinical presentation of an 81-year-old male with knee swelling.
  • Radiographic imaging to assess calcification patterns.
  • Histopathological examination of resected tissue.
  • Laboratory tests for renal function and parathyroid hormone levels.

Main Results:

  • X-ray suggested bursal chondromatosis or ectopic calcification.
  • Histopathology confirmed tumoral calcinosis.
  • Laboratory findings indicated renal insufficiency and secondary hyperparathyroidism.

Conclusions:

  • Tumoral calcinosis is a rare cause of infrapatellar swelling.
  • A combination of imaging, histology, and biochemical analysis is crucial for diagnosis.
  • The condition is associated with metabolic disturbances like secondary hyperparathyroidism.