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The Effect of Computerized Alerts on Prescribing and Patient Outcomes: A Systematic Review
Brian G Bell1, Adam Khimji2,3, Basharat Hussain3
1NIHR Greater Manchester Patient Safety Research Collaboration, University of Nottingham, Nottingham, United Kingdom.
Applied Clinical Informatics
|May 26, 2025
Summary
Computerized alerts significantly improve clinician prescribing practices and show benefits for patient outcomes. These systems, including drug-allergy and dose range alerts, are valuable tools in healthcare.
Area of Science:
- Health Informatics
- Clinical Decision Support
- Pharmacovigilance
Background:
- Growing body of research on computerized alerts' impact on prescribing and patient outcomes.
- Need to synthesize evidence on the effectiveness of these systems.
Purpose of the Study:
- To examine the impact of computerized alerts on clinician prescribing and patient outcomes.
- To identify specific alert types associated with improved prescribing.
Main Methods:
- Systematic literature search of Medline, Embase, and PsychINFO databases since 2009.
- Data extraction from 69 studies focusing on alerts at the point of prescribing.
- Analysis of both randomized controlled trials (RCTs) and non-RCTs.
Main Results:
- 84.1% of studies reported beneficial effects of computerized alerts on prescribing.
- Drug-allergy, dose range, and formulary alerts showed high rates of prescribing improvement.
- 70% of studies reporting on patient outcomes demonstrated a beneficial effect.
Conclusions:
- Computerized alerts generally have a positive impact on prescribing.
- Benefits are observed across various alert types and study designs.
- Continued development and implementation of these systems are supported.
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