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Spinal anaesthesia with meperidine as the sole agent
Canadian Anaesthetists' Society Journal
|September 1, 1985
Summary
Intrathecal meperidine effectively provided anesthesia for perineal and inguinal surgeries, offering prolonged postoperative pain relief for up to seven days. This study highlights its potential as a sole anesthetic agent, especially for painful procedures.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Spinal anesthesia is crucial for various surgical procedures.
- Alternative anesthetic agents are sought for prolonged postoperative analgesia.
Purpose of the Study:
- To evaluate the efficacy and safety of intrathecal meperidine as a sole anesthetic agent.
- To assess the duration of sensory/motor block and postoperative analgesia.
- To identify potential side effects of intrathecal meperidine.
Main Methods:
- Twenty male patients (ASA I-II) received 1 mg/kg intrathecal meperidine.
- Procedures involved surgery in the perineal or inguinal areas.
- Sensory and motor block onset, surgery duration, and postoperative pain were monitored.
Main Results:
- Complete sensory and motor block achieved within 10 minutes.
- Surgery proceeded with complete analgesia (duration 39.7 ± 14 min).
- Prolonged postoperative analgesia observed, with some patients requiring no additional narcotics for up to 7 days.
Conclusions:
- Intrathecal meperidine (1 mg/kg) is effective as a sole agent for spinal anesthesia.
- It provides prolonged postoperative analgesia, beneficial for painful surgeries like hemorrhoidectomy.
- Meperidine serves as a viable alternative anesthetic when local anesthetics are unavailable.