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Updated: Jun 12, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
Published on: April 1, 2019
A bibliometric evaluation of scientific productivity in meibomian gland dysfunction research
Bedia Kesimal1, Sücattin İlker Kocamış1
1Ophthalmology Department, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Clinical Relevance:
Meibomian gland dysfunction (MGD) is a major contributor to dry eye disease, affecting a large proportion of the population and leading to significant discomfort and ocular surface complications. Understanding trends in MGD research, including advancements in diagnostic technologies, therapeutic approaches, and interdisciplinary collaborations, is critical for improving clinical practices.
Background:
This study aims to perform a bibliometric analysis on MGD to assess the current international status of meibomian gland dysfunction research and identify the most influential contributors (journals, countries, authors) and research topics in this field.
Methods:
Data from studies on MGD were obtained using the Web of Science Core Collection on Science Citation Index Expanded database. Information regarding journals, titles, text, keywords, references, citations, author names, author institutions, and countries was recorded for each publication. The data were analysed using features of the Web of Science Core Collection website and the VOSviewer visualisation tool.
Results:
A total of 1313 articles published between 1980 and 2024 were identified. The number of articles published in the last 10 years was found to be 3.01 times greater than in all previous years combined. The United States and China were the most productive countries, with the highest number of articles and citations. The most productive institutions were located in the United States and Japan. The most prolific author was Reiko Arita. The most frequently cited article was titled 'The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on Anatomy, Physiology, and Pathophysiology of the Meibomian Gland'. Recent and emerging keywords include 'intense pulsed light', 'meibography', 'lipiflow', 'artificial intelligence', 'meibogenesis', 'lipidomics' and 'human meibomian gland epithelium', reflecting current trends in MGD research.
Conclusions:
This study provides an overview of the current status and trends in MGD research, which may help clinicians and researchers better understand this field and predict its future directions.

