Related Experiment Video
Updated: Sep 20, 2025
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Predicting Mortality in Necrotising Otitis Externa: The Charlson Comorbidity Index
Dalton Barham1, Stan Mckenzie2, Glen Watson1
1Shefield Teaching Hospitals Foundation Trust, Shefield, UK.
Introduction:
Necrotising Otitis Externa (NOE) is a severe infection of the ear canal and skull base with a significant morbidity and mortality. There is a limited evidence base to help prognosticate in NOE, focused mainly on disease volume and associated damage. In this retrospective case series, we examined the potential use of the Charlson comorbidity index (CCI) in patients with confirmed NOE to determine its potential use as an additional prognostic indicator.
Methods:
Retrospective cohort analysis of 87 patients diagnosed with NOE over a 6-year period at a tertiary centre. We calculated the CCI for these patients and collected mortality data at 1 year. A logistic regression was used to analyse the data.
Results:
The mean CCI was 5.9. A higher score was a reliable indicator of 1-year mortality for patients with NOE with an odds ratio of 1.34 (p = 0.028).
Conclusion:
The CCI can be considered as a potential adjunct in patients presenting with NOE to guide prognostication and inform decision-making with patients.
Related Concept Videos
01:30Pneumonia III: Complications and Assessment
01:21Cancer Survival Analysis
01:20Actuarial Approach
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:21Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include: