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Harmonic Nanoparticles for Regenerative Research
Published on: May 1, 2014
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Design of a nonlinear metastructure for temperature detection and biosensing based on the second harmonic generation
Cheng Yang1, Yu-Xin Wei1, Heng-Jing Liu1
1College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing, 210023, China. hanlor@njupt.edu.cn.
Journal of Materials Chemistry. B
|May 27, 2025
Summary
A novel nonlinear metastructure enhances second harmonic generation for precise temperature sensing and refractive index biosensing. This technology offers new possibilities for optical detection and biomedical applications.
Area of Science:
- Nonlinear optics
- Metamaterials
- Biomedical sensing
Background:
- Second harmonic generation (SHG) in ferroelectric crystals is sensitive to temperature and refractive index (RI) changes.
- Nonlinear metastructures (NM) can enhance SHG for improved optical sensing capabilities.
Purpose of the Study:
- To design a one-dimensional nonlinear metastructure (NM) for enhanced SHG.
- To utilize the NM for wide-range temperature detection and refractive index (RI) biosensing of liver tissues.
Main Methods:
- Fabrication of a one-dimensional nonlinear metastructure using periodically poled lithium niobate crystals.
- Incident tunable fundamental electromagnetic waves near 241.067 THz for temperature sensing and near 273 THz for RI sensing.
- Analysis of second harmonic wave (SHW) generation for signal detection.
Main Results:
- Achieved wide-range temperature detection from 25-105 °C with a sensitivity of 0.32% per °C.
- Demonstrated RI biosensing for distinguishing liver tissues with a sensitivity of 14.75 THz per RIU over a range of 1.3463 to 1.3655.
- Observed significant SHG enhancement in the visible to near-infrared spectral range.
Conclusions:
- The proposed NM effectively integrates SHW generation with optical detection and sensing.
- This technology provides new insights for SHW applications in temperature monitoring and biomedical diagnostics.
- The NM shows potential for advanced optical sensing and biosensing in various fields.
