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Dental Resin Composites Modified with Chitosan: A Systematic Review
Wojciech Dobrzyński1, Paweł J Piszko2, Jan Kiryk3
1Department of Dentofacial Orthopedics and Orthodontics, Division of Facial Abnormalities, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.
Marine Drugs
|May 27, 2025
Summary
Chitosan enhances dental resin composites
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
- Nanotechnology in Dentistry
Background:
- Dental resin composites are widely used restorative materials.
- Improving their mechanical and antibacterial properties is crucial for enhanced clinical performance.
- Chitosan, a natural biopolymer, has emerged as a potential additive.
Purpose of the Study:
- To systematically review the effects of incorporating chitosan into dental resin composites.
- To evaluate impacts on mechanical, antibacterial, and physicochemical properties.
- To identify optimal chitosan concentrations for beneficial outcomes.
Main Methods:
- A systematic literature search was performed across PubMed, Scopus, and Web of Science.
- In vitro dental studies evaluating chitosan as a composite additive were included.
- Data extraction and quality assessment were conducted by multiple reviewers.
Main Results:
- Seventeen studies were included, with chitosan concentrations from 0.25 wt% to 20 wt%.
- Antibacterial activity against key oral bacteria was confirmed.
- Lower chitosan concentrations improved fracture toughness, hardness, and compressive strength.
- Higher concentrations negatively affected flexural strength, microleakage, and shear bond strength (SBS).
Conclusions:
- Chitosan-modified dental resin composites show promise for antibacterial and mechanical benefits at low concentrations.
- Higher chitosan levels may compromise mechanical and adhesive properties.
- Further research is needed on clinical implications and fluoride release, alongside standardized methodologies.

