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[New WHO Reporting System for Lung Cytopathology]
1Institut für Pathologie, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland. marianne.engels@uk-koeln.de.
Pathologie (Heidelberg, Germany)
|May 27, 2025
Summary
The new World Health Organization Reporting System for Lung Cytopathology offers a standardized international approach to respiratory tract cytology. It uses five diagnostic categories based on cytomorphology, making it accessible for resource-limited settings.
Area of Science:
- Pathology
- Cytopathology
- Oncology
Context:
- The need for a standardized international reporting system for lung cytopathology.
- Existing systems may not be universally applicable, especially in resource-limited settings.
- The importance of cytomorphology in diagnosing respiratory tract conditions.
Purpose:
- To introduce the new World Health Organization Reporting System for Lung Cytopathology.
- To establish a standardized international framework for respiratory tract cytology reporting.
- To ensure applicability in resource-limited countries.
Summary:
- The World Health Organization Reporting System defines five diagnostic categories: insufficient/inadequate/non-diagnostic, benign, atypical, suspicious for malignancy, and malignant.
- Classification relies on cytomorphology, making the system accessible globally.
- Key diagnostic features, differential diagnoses, and ancillary testing (immunocytochemistry, molecular pathology) are detailed.
Impact:
- Facilitates consistent and reliable reporting of lung cytology specimens worldwide.
- Improves diagnostic accuracy and communication among pathologists and clinicians.
- Supports better patient management and research in lung cancer and other respiratory diseases.

