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Management of cervical artery dissection: new evidence and future directions

Josefin E Kaufmann1,2, Lukas Mayer-Suess3, David Seiffge4

  • 1Department of Neurology and Stroke Center, University Hospital Basel and University of Basel, Basel, Switzerland. Josefin.kaufmann@usb.ch.

Journal of Neurology
|May 27, 2025
PubMed

Insights

Cervical artery dissection (CeAD) is a key cause of stroke in young adults. This review covers recent CeAD management, including risk factors and mental health, and suggests future research directions.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Stroke Research

Background:

  • Cervical artery dissection (CeAD) is a primary cause of ischemic stroke in young adults.
  • The pathogenesis of CeAD is not fully understood, but patient care has improved.
  • Recent advancements focus on hyperacute and subacute management strategies.

Purpose of the Study:

  • To provide an updated overview of current evidence on CeAD management.
  • To highlight under-addressed aspects such as vascular risk factors and mental health in CeAD.
  • To propose future research directions for improved patient outcomes and disease understanding.

Main Methods:

  • Literature review of recent evidence on CeAD management.
  • Synthesis of information on hyperacute and (sub-)acute treatment strategies.
  • Identification of knowledge gaps and areas for future investigation.

Main Results:

  • Evidence on hyperacute and (sub-)acute CeAD management has advanced.
  • Vascular risk factors and mental health are critical but often overlooked aspects of CeAD.
  • Gaps in understanding necessitate further research.

Conclusions:

  • Updated management strategies for CeAD are emerging.
  • Comprehensive care for CeAD should integrate vascular risk factor management and mental health support.
  • Future research is crucial to enhance CeAD patient outcomes.

Keywords:
Antithrombotic treatmentCervical artery dissectionHyperacute treatmentMental healthStrokeVascular risk factors

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