Digital Therapeutics in China: Comprehensive Review
Nan Jiang1,2,3,4,5, Xiru Yu6,7, Yuxi Yang8
1School of Healthcare Management, Tsinghua University, Beijing, China.
Journal of Medical Internet Research
|May 27, 2025
Summary
China
Area of Science:
- Digital health innovations
- Software-driven medical interventions
- Evidence-based treatment strategies
Background:
- Digital therapeutics (DTx) offer personalized, evidence-based treatments.
- China's tech adoption and policies position it for DTx leadership.
- Challenges include trial standardization, regulation, and reimbursement.
Purpose of the Study:
- Analyze China's DTx landscape: clinical trials, products, regulations, and reimbursement.
- Provide insights for global DTx development and healthcare integration.
- Assess the evolving DTx ecosystem and its global implications.
Main Methods:
- Systematic review and meta-analysis of DTx clinical trials (PubMed, etc.).
- Scoping review of commercial DTx products via NMPA database.
- Manual review of regulatory policies and analysis of pricing/reimbursement models.
Main Results:
- 96 DTx trials identified; cognitive disorders and diabetes most studied.
- Meta-analysis showed significant cognitive function improvement (SMD 0.65).
- 97 active DTx solutions; cognitive, ophthalmic, and respiratory diseases targeted.
- China uses general medical device regulations; regional policies support growth.
- Diverse pricing and reimbursement models observed.
Conclusions:
- China shows DTx progress but needs standardized trials and streamlined regulation.
- Targeted indications, trial standardization, and clear regulations drive adoption.
- China's DTx experience offers lessons for emerging digital health ecosystems.
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