Legg-Calvé-Perthes disease in a family: genetic or environmental
Clinical Orthopaedics and Related Research
|October 1, 1985
Insights
Legg-Calvé-Perthes disease (LCPD) affected four males in one family, aged 3-8 years. This high incidence suggests potential genetic or environmental factors contributing to LCPD etiology.
Area of Science:
- Orthopedics
- Genetics
- Pediatrics
Background:
- Legg-Calvé-Perthes disease (LCPD) is a hip disorder affecting children.
- The exact cause of LCPD remains unclear, with both genetic and environmental factors suspected.
Abstract:
This is a case report of a family in which Legg-Calvé-Perthes disease (LCPD) occurred in four members. All the patients were male and between the ages of three and eight years. This unusually high incidence in one family raises questions about the genetic versus the environmental factors in the etiology of LCPD.
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