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Chronic Intravenous Inotropic Support as Bridge to Surgical Therapies in Patients With Sarcoidosis-Related

Johana Fajardo1, Rachel Barish2, Francisca Bermudez3

  • 1Duke University Medical Center.

The American Journal of Cardiology
|May 27, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
cardiomyopathychronic intravenous inotropic supportheart failureinotropessarcoidosis

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Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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