Live birth in a twin pregnancy with a complete hydatidiform mole and a coexisting normal fetus

Co-presentation of complete mole with live pregnancy is very rare, few cases with live birth were reported. The diagnosis requires a high index of suspicion, which is important to set the management plan antenatal, intrapartum, postnatal and neonatal.Our patient conceived during follow-up for previous partial molar pregnancy. Early pregnancy scan showed a gestational sac with cystic spaces. Ultrasound scans by fetal medicine specialists revealed a normally developing fetus with partly multicystic placenta. She was delivered by caesarean section at 31 weeks due to abdominal pain and increasing size of the theca lutein cysts. Placental histology and cytogenetics confirmed the diagnosis. Further course of care was uneventful.Incidence of the above-mentioned condition is 1 in 20 000 to 100 000. This is a high-risk pregnancy with multiple maternal, fetal and neonatal complications. The suggested management plan involves a multidisciplinary team and individualised care with close maternal and fetal monitoring.