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Mini-subcostal incision technique for open radical nephrectomy: A practical alternative for complex renal masses
Kyle A Blum1, Chun Huang1, A Ari Hakimi1
1Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Urologic Oncology
|May 27, 2025
Summary
The mini-subcostal open radical nephrectomy (msRN) technique offers a viable alternative for complex kidney masses, demonstrating favorable outcomes and preserving open surgical skills. This approach is effective for selected cases.
Area of Science:
- Urology
- Surgical Oncology
- Nephrology
Background:
- Complex renal masses often require challenging surgical interventions.
- Traditional open and minimally invasive surgery (MIS) have limitations for certain cases.
- Preserving open nephrectomy skills is crucial for managing selected complex renal masses.
Purpose of the Study:
- To describe the mini-subcostal open radical nephrectomy (msRN) technique.
- To evaluate the renal function, perioperative, and oncological outcomes of msRN.
- To present msRN as a practical alternative for complex renal masses.
Main Methods:
- Retrospective analysis of patients undergoing msRN from 2013 to 2016.
- Utilized an 8 to 12 cm mini-subcostal incision.
- Analyzed clinicopathologic, perioperative, renal function metrics, and survival using statistical models.
Main Results:
- 193 patients with complex renal masses (median tumor size 7.2 cm, 67.9% ≥pT3) were analyzed.
- Median incision length was 10 cm; median operative time was 123 minutes.
- Median estimated glomerular filtration rate (eGFR) decreased by 34.1% with no dialysis requirements; 30-day complication rate was 18.1%.
Conclusions:
- The msRN technique provides favorable outcomes for complex renal masses.
- msRN is a practical alternative to traditional open and MIS approaches.
- This approach supports the continued relevance of open surgical techniques for specific renal cases.

