Cohort Changes in Cognitive Function Among Mexican Older Adults from 2001 to 2021

  • 0Department of Community Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, California, USA.

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Summary

This summary is machine-generated.

Older adults in Mexico experienced slower cognitive decline in more recent cohorts. Multimorbidity

Area Of Science

  • Gerontology
  • Cognitive Neuroscience
  • Public Health

Background

  • Multimorbidity, defined as having two or more chronic conditions, is linked to accelerated cognitive decline in older adults.
  • Longitudinal data on cognitive decline and multimorbidity in low- and middle-income countries, such as Mexico, are scarce.

Purpose Of The Study

  • To investigate cohort differences in the annual rate of cognitive decline among older Mexican adults.
  • To determine if the association between multimorbidity and cognitive decline varies between two distinct birth cohorts.

Main Methods

  • Analysis of two 10-year birth cohorts (Cohort 1: 1941-1951; Cohort 2: 1952-1962) with baseline ages 50-60.
  • Three waves of data collection over 10-year periods for each cohort (Cohort 1: 2001, 2003, 2012; Cohort 2: 2012, 2015, 2021).
  • Growth curve models were employed to assess annual changes in global cognitive function scores (GCFS) and cohort differences.

Main Results

  • The earlier cohort (Cohort 1, baseline 2001) exhibited a significantly faster average annual rate of cognitive decline (GCFS) compared to the later cohort (Cohort 2, baseline 2012).
  • The association between multimorbidity and the rate of cognitive decline did not significantly differ between the two cohorts when controlling for potential confounders.

Conclusions

  • The observed slower cognitive decline in the more recent cohort suggests potential benefits from improved educational attainment and enhanced cognitive reserve.
  • Improvements in healthcare access over recent decades may have mitigated the adverse effects of multimorbidity on cognitive function, explaining the lack of cohort differences in this association.
  • Findings highlight evolving patterns of cognitive aging and the impact of multimorbidity in the Mexican population.

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