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Primary acquired sideroblastic anaemia and myeloproliferative disease: a report on three cases
Clinical and Laboratory Haematology
|January 1, 1985
Abstract:
Three patients who presented with primary acquired sideroblastic anaemia (PASA) later developed myelofibrosis (MF). As both are clonal disorders a second mutation is suggested.
Insights
Primary acquired sideroblastic anaemia (PASA) can progress to myelofibrosis (MF). This suggests a potential second mutation in these clonal blood disorders.
Area of Science:
- Hematology
- Oncology
- Genetics
Background:
- Primary acquired sideroblastic anaemia (PASA) is a rare clonal bone marrow disorder.
- Myelofibrosis (MF) is a serious myeloproliferative neoplasm characterized by bone marrow fibrosis.
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