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Updated: Feb 21, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
The association between four neighborhood disadvantage indices and child chronic health classifications
Kahir Jawad1, Yana B Feygin2, Michelle Stevenson3,4
1Norton Children's Research Institute affiliated with the University of Louisville School of Medicine, Louisville, KY, USA. Kahir.jawad@nortonhealthcare.org.
Insights
Neighborhood disadvantage is linked to higher rates of complex chronic diseases in children. Even non-complex chronic diseases show increased odds with declining neighborhood opportunity, highlighting the impact of social determinants on child health.
Area of Science:
- Public Health
- Social Epidemiology
- Health Disparities
Background:
- Neighborhood characteristics are recognized social determinants of health.
- Understanding the link between neighborhood environment and child chronic conditions is crucial.
Purpose of the Study:
- To examine the distribution and associations between child chronic health conditions and four common neighborhood indices.
- To assess how different neighborhood measures relate to medical complexity classifications in children.
Main Methods:
- Utilized data from 115,738 children with outpatient visits and valid addresses.
- Categorized outcomes into no chronic disease (N-CD), non-complex chronic disease (NC-CD), and complex chronic disease (C-CD).
- Calculated four neighborhood indices: Child Opportunity Index (COI), Area Deprivation Index (ADI), Neighborhood Disadvantage Index, and Social Vulnerability Index (SVI), using multinomial logistic regression.
Main Results:
- All four neighborhood indices were correlated (r=0.80-0.92).
- Children in disadvantaged neighborhoods had higher odds of C-CD (5-39%) and NC-CD (8-31%) compared to those in advantaged neighborhoods.
- The association between neighborhood disadvantage/low opportunity and chronic disease classification strengthened as disadvantage increased or opportunity decreased.
Conclusions:
- All evaluated neighborhood indices showed associations with medical complexity classifications in children.
- The Area Disadvantage Index (ADI) and Child Opportunity Index (COI) showed incremental increases in C-CD odds with decreasing neighborhood opportunity.
- The choice of neighborhood index should align with study objectives and the specific population under investigation.
Background:
Neighborhood advantage/disadvantage is a social determinant of health. We aimed to examine the distribution and associations between child chronic health conditions and four commonly used indices.
Methods:
Children with outpatient visits and valid addresses (n = 115,738) were included and outcomes were categorized as having no chronic disease (N-CD), non-complex chronic disease (NC-CD), and complex chronic disease (C-CD). Four measures of neighborhood characteristics (Child Opportunity Index, Area Deprivation Index, Neighborhood Disadvantage Index, Social Vulnerability Index were calculated from census data. Separate multinomial logistic regression models were used.
Results:
The indices' scores were correlated (r = 0.80-0.92). Children in low opportunity or high disadvantage/deprivation/vulnerability neighborhoods were more likely to be diagnosed with C-CD than those in high opportunity or low disadvantage/deprivation/vulnerability neighborhoods. The increased odds ranged from 5% to 39%. The adjusted odds of NC-CD were found to increase by 8-31% as the neighborhood opportunity declined or the disadvantage/deprivation/vulnerability increased, across all indices. The association grew stronger as neighborhood opportunity decreased, or disadvantage/deprivation/vulnerability increased for all four indicators.
Conclusions:
Each instrument was associated with medical complexity classifications, but the magnitude of the associations differed slightly. The rationale for choosing a measure of neighborhood characteristics should be based on the study's aims and population.
Impact:
This study evaluates the associations of four commonly used neighborhood indices with medical complexity classifications. All indices were associated with study outcomes. The Area Disadvantage Index (ADI) and Child Opportunity Index (COI) demonstrated incremental increases in the odds of receiving a classification of complex chronic disease (C-CD) compared to no chronic disease (N-CD) as neighborhood opportunity decreased or the disadvantage/deprivation/vulnerability increased. Being classified with a non-complex chronic disease (NC-CD) compared to N-CD, only the association with the COI increased incrementally at each level of opportunity. Study outcomes and index characteristics must be considered when designing studies.
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