Neuronal firing pattern following amygdaloid kindling in unrestrained rats

Chronic recordings of amygdaloid neurons were performed on freely moving rats following kindling. Satisfactory recordings were obtained from 22 amygdaloid neurons of the contralateral amygdala before, during, and after unilateral kindling. Kindling stimulations were given once per hour. Seven cells disappeared during kindling. Seven cells were recorded during the full course of kindling. These units showed (a) an increase in spontaneous firing, (b) a development of high-frequency bursts (the peak interval of the interval histogram decreased from 18 to 2 ms), and (c) high-frequency firings during spontaneous activity that were similar to the firings recording during afterdischarge.