Related Experiment Video
Updated: Jan 18, 2026

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
Bouquet of flower calcification in renal tubular acidosis
Somdatta Giri1, Shaik Mohammad Tahaseen2, Shinjan Patra1
1Department of Endocrinology at AIIMS Kalyani, Nadia, West Bengal, India.
Abstract:
Nephrocalcinosis, marked by calcium phosphate deposition in the kidneys, is often linked to distal renal tubular acidosis (dRTA). While typically driven by hypercalciuria, hyperphosphaturia can also promote crystal formation in alkaline urine. A 24-year-old female with recurrent fractures and hip pain presented with hypokalemia, metabolic acidosis, and hyperphosphaturia but without hypercalciuria. Imaging revealed medullary nephrocalcinosis and osteomalacia, secondary to dRTA. Potassium citrate improved her condition. This case emphasizes early recognition of dRTA to prevent renal and skeletal complications.
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